Cosplay Girls, San Diego Comic-Con 2013, California, United States

Comic-Con International has served as the setting for Mark Hamill's Comic Book: The Movie, and for an episode of the HBO television series Entourage, the latter of which, while set at the event, was not filmed there. Comic-Con also served as an excuse for the fictional characters Seth Cohen and Ryan Atwood's trip to Tijuana, Mexico in the first season of TV series The O.C. The convention also featured prominently as a setting for the Numb3rs episode "Graphic". In Season 4 of Beauty and the Geek, an episode was featured where the contestants traveled to Comic-Con 07 and were given a challenge to create their own superheroes. In an episode of Punk'd, Hilary Swank gets Punk'd after an "attack from talking robot". In Season 5, episode six, of the Showtime show Weeds, attendees from Comic-Con 2009 are seen in Silas and Doug's medicinal marijuana club.
It was reported that a mock-up of the external area near Hall D of the Convention Center depicting Comic-Con would be shown in the movie Paul which stars Simon Pegg and Nick Frost. Issue No. 72 of The Invincible Iron Man (1974) was set at the July–August 1974 Comic-Con at the El Cortez Hotel, and featured cameos by a few of the special guests.
Comic-Con is mentioned in the CBS television show The Big Bang Theory in several episodes, and in NBC's Chuck in the episode "Chuck Versus the Sandworm", as an event the characters enjoy attending. On the Futurama episode "Lrrreconcilable Ndndifferences", the main characters attend the 3010 convention (with it being referred to as "Comic-Con Intergalactic" and the iconic eye logo now sporting multiple eyes), where Fry looks for approval for his own comic while Bender attends a panel from Matt Groening (creator of Futurama as well as The Simpsons) on his new show "Futurella" (a twist on the title of the show and a parody of its cancellation by Fox).
In "It's My Party and I'll Bang If I Want To", an episode of the 2011 season of The Real World: San Diego, the cast attends Comic-Con made up as zombies in order to pass out promotional flyers for the House of Blues, where they worked as part of their season work assignment. Filmmaker Morgan Spurlock released a 2011 documentary feature film set at the convention, Comic-Con Episode IV: A Fan's Hope. Writer Robert Salkowitz also used the 2011 Comic-Con as a backdrop for his book Comic-Con and the Business of Pop Culture, an analysis of the comics industry's 21st-century dilemmas and what the future may hold.