Big Mouth Babes

The nasolabial folds are the deep creases of tissue that extend from the nose to the sides of the mouth. One of the first signs of age on the human face is the increase in prominence of the nasolabial folds.
Cultural aspects
Lips can be adorned with lipstick or lip gloss, although in most cultures, this is typically only practiced by females. Both men and women, however, apply lip balm in order to soothe chapped or dry lips.