Space Shuttle Atlantis

Astronaut Michael Massimino who flew on STS-125 mission became the first person to use Twitter in space in May 2009.
Having flown aboard Atlantis as part of the STS-132 crew in May 2010 and Discovery as part of the STS-133 crew in February/March 2011, Stephen Bowen became the first NASA astronaut to be launched on consecutive missions.